Cymbalta’s Side Effects On Sleeping
Duloxetine is a drug made by the Eli Lily company. It is sold under the trade name of Cymbalta. **According to a summary published in the journal “Expert Review of Neurotherapeutics,” duloxetine may be useful in several medical conditions 1. These disorders include depression, anxiety and pain. Cymbalta is a safe and effective medication. Yet it can change both sleep quality and sleep quantity. The effects of duloxetine on sleep depend upon the population tested 2.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
What Effects Will It Have On My Body
A side effect of duloxetine can be not feeling as hungry as normal, which might lead to weight loss.
In studies, some children and young people aged under 18 who took duloxetine had some weight loss at first, but after six months of treatment they went back to normal compared with other people of the same age.
It is very difficult to know how it will affect each person who takes it.
Talk to your doctor about this if it worries you.
How Much Will I Take
For depression, anxiety and nerve pain, duloxetine comes in 30mg and 60mg capsules.
For stress urinary incontinence, duloxetine comes in 20mg and 40mg capsules.
How much you take will depend on what you’re taking it for:
- depression – the starting dose is 60mg a day and can be increased to 120mg a day
- anxiety – the starting dose is 30mg a day and can be increased to 60mg a day
- nerve pain – the starting dose is 60mg a day and can be increased to 60mg twice a day
- stress urinary incontinence – the starting dose is 20mg twice a day and can be increased to 40mg twice a day after 2 weeks
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Is Weight Gain One Of Cymbaltas Side Effects
But keep in mind that depression, which Cymbalta is used to treat, can cause weight changes. So, if you have weight changes while youre taking Cymbalta, this could be due to Cymbalta reducing your depression symptoms. Weight changes may not be caused by Cymbalta itself.
If youre concerned about weight gain while taking Cymbalta, we recommend talking with your medical professional. They can suggest ways to maintain a weight thats healthy for you.
Are Cymbalta Or Effexor Safe To Take If I Am Pregnant Or Breastfeeding
- Duloxetine is excreted into the milk of lactating women. Because the safety of duloxetine in infants is not known, breastfeeding while on duloxetine is not recommended.
- The effects of venlafaxine on the fetus during pregnancy are unknown.
- It is not known if venlafaxine is secreted in breast milk, and therefore, if it may have an effect on nursing infants.
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Duloxetine Side Effects: Short
Authored by Sharon Levy, MD, MPH
Cymbalta has a variety of both minor and severe adverse effects. While some patients can tolerate the most common Duloxetine side effects well, many others are forced to switch to a different drug. It is, therefore, essential to learn about Duloxetine warnings, the adverse effects of taking Cymbalta and discuss them with a doctor before the treatment begins.
Is Cymbalta Or Effexor More Effective
The effectiveness of Cymbalta or Effexor depends on the condition being treated. Very few studies have directly compared Cymbalta and Effexor. However, when compared to placebo, Cymbalta and Effexor are both more effective for treating conditions like major depression.
One study pooled several clinical trials and found that venlafaxine is a better short-term treatment option for major depression than duloxetine. Venlafaxine, the active ingredient of Effexor, may also be preferred for those who donât respond well to initial treatment with selective serotonin reuptake inhibitors or tricyclic antidepressants . However, the study found that there were no significant differences in response and response rate between duloxetine and venlafaxine.
Another systematic review compared venlafaxine, duloxetine, and other antidepressants like paroxetine, fluoxetine, and fluvoxamine. Compared to the other options, venlafaxine was found to be one of the more effective antidepressants. However, both venlafaxine and duloxetine were ranked as some of the least tolerable antidepressants, regarding side effects.
Consult a healthcare provider who specializes in psychiatry for the best treatment option for you.
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Inpatient Drug Rehab Vs Outpatient Drug Rehab For Cymbalta Treatment
A person recovering from Cymbalta abuse or polysubstance abuse may choose to enroll in a residential rehab program or an outpatient rehab program. Most people who need medical treatment for Cymbalta withdrawal will not need the intensive treatment a residential rehab program provides. However, an outpatient rehab program can be extremely helpful, especially for someone who abuses multiple drugs including Cymbalta or who has a history of substance abuse problems.
When choosing between a residential drug rehab program and an outpatient drug rehab program, its helpful to know the difference between the two.
The cost of a Cymbalta rehab program will also vary depending on several factors like:
- The type of Cymbalta rehab program and services offered
- The facilitys amenities
Payment options for inpatient or outpatient drug rehab may include health insurance benefits, Employee Assistance Program benefits, private financed loans, and out-of-pocket payments.
Nasal Decongestants Or Oral Decongestants
Decongestants can come in handy when youre suffering from a stuffy nose. They can be taken as a nasal spray, like , or as an oral decongestant, like . But one downside is that decongestants can cause insomnia.;
If youre using a decongestant, its probably just for a short period of time, so you may decide to push through the nighttime annoyance until you dont need it anymore. You could also consider an alternative, drug-free option like a saline nasal spray or an antihistamine nasal spray like .;
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How Are Sleep And Depression Linked
Depression is a mood disorder that is characterized by sadness or feeling blue along with a series of physical symptoms such as low energy, disrupted sleep, and appetite changes. Nearly everyone feels normal sadness or feels down from time to time. Sometimes, however, the sad feelings become intense, last for long periods of time, and involve other physical symptoms that prevent a person from leading a normal life. These feelings often lead to a medical diagnosis of clinical depression.
An inability to sleep that lasts over a long period of time is also an important clue that someone may be depressed.
Are Certain Cymbalta Side Effects Specific To Older Adults
Yes, adults ages 65 and older may have a higher risk for certain side effects of Cymbalta.
For example, compared with younger people, older people may have a higher risk for:
To learn more about how your age affects your risk for side effects from Cymbalta, you can talk with your medical professional.
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How Does Cymbalta Make You Feel
Cymbalta doesnt make you feel high or euphoric, like you may feel from using illicit drugs. If you have questions about how Cymbalta may affect you, talk with your doctor or pharmacist.
Dosage For Chronic Musculoskeletal Pain
The recommended Cymbalta dose for treating chronic musculoskeletal pain* in adults is 60 mg once daily.
Youll start by taking 30 mg once daily for a week. Then, assuming you respond well to the drug, your doctor will increase your dose to 60 mg once daily. Doses above 60 mg arent recommended for treating this condition.
* With chronic musculoskeletal pain, you have ongoing pain in your bones, muscles, ligaments, nerves, and tendons.
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Cautions With Other Medicines
Some medicines and duloxetine can interfere with each other and increase the chances of you having side effects.
Tell your doctor if you’re taking:
- any other medicines for depression – some rarely used antidepressants can interfere with duloxetine to cause very high blood pressure even after you have stopped taking them
- medication used to thin the blood, such as warfarin
- diazepam, chlorphenamine or other medication that can make you feel more sleepy
- tramadol â this can increase the chances of you having certain side effects
Mixing duloxetine with herbal remedies and supplements
Do not take the herbal remedy St John’s wort while you’re being treated with duloxetine, as this will increase your risk of side effects.
Does Cymbalta Cause Hair Loss
One of the most surprising and frustrating Duloxetine side effects is hair loss. Patients rarely expect it because it is not officially listed as a side effect of Duloxetine. So when it happens, the lack of information makes them think its caused by something else. However, hair loss on the drug has been reported by many individuals. Although the hair loss isnt usually too significant, the symptom usually goes away after the dose is reduced. Talk to the doctor about adjusting the course of treatment if substantial hair loss is noticed. General hair loss that increased during treatment may stabilize once the patient is used to taking the drug or once the dose is adjusted.
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How Long Do Side Effects From Cymbalta Last
How long side effects from Cymbalta last can vary depending on the side effect.
Also, your risk for certain side effects may be higher when you first start taking the drug. For example:
- Your risk for suicidal thoughts or behaviors may be highest in your first few months of taking Cymbalta or after your dose is changed. However, this can occur at any time while taking Cymbalta.
- Your risk for orthostatic hypotension may be highest in your first week of taking Cymbalta.
Some side effects may go away once the drug is stopped. However, other side effects, like liver failure, may not go away if you stop the drug.
If you have questions about your risk for side effects with Cymbalta, talk with your doctor or pharmacist.
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Jena Hilliard earned her Bachelors of Arts degree from the University of Central Florida in English Literature. She has always had a passion for literature and the written word. Upon graduation, Jena found her purpose in educating the public on addiction and helping those that struggle with substance dependency find the best treatment options available.
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- Drugs.com. . Cymbalta. Retrieved on 12th June 2019 from
- Drugs.com. . Cymbalta Side Effects: Cause For Concern? Retrieved on 12th June 2019 from
- Evans, Elizabeth A. . Abuse and Misuse of Antidepressants. Retrieved on 13th June 2019 from
- National Alliance on Mental Illness. . Duloxetine . Retrieved on 13th June 2019 from
- Web MD. . Cymbalta. Retrieved on 13th June 2019 from
All of the information on this page has been reviewed and verified by a certified addiction professional.
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Cymbalta And Suicidal Thoughts
The tendency to cause suicidal behaviors is one of the most dangerous aftereffects of Cymbalta. This property is not exclusive to this drug and is displayed by many antidepressants. They can sometimes make depression and anxiety disorder worse. According to Duloxetine warnings, patients should be monitored closely during the first weeks of treatment to ensure there arent increased suicidal thoughts.
There is also a link between Duloxetine and suicide when patients change the dose or stop taking the medication without supervision. Therefore, if suicidal thoughts are frequent, its advisable to get help in the drug facilities.
Cymbalta Vs Effexor: Differences Similarities And Which Is Better For You
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Cymbalta and Effexor are brand-name medications used to treat psychiatric conditions such as depression and anxiety. They are usually prescribed as antidepressants to help relieve the symptoms of major depressive disorder. Symptoms of major depressive disorder may include persistent sadness and a severe loss of interest in daily activities.
Cymbalta and Effexor both belong to a class of drugs called serotonin and norepinephrine reuptake inhibitors . They work by increasing the availability of serotonin and norepinephrine in the brain. These chemicals, or neurotransmitters, are believed to play a role in the occurrence of mental health disorders.
For the purposes of this comparison, the name Effexor may also refer to Effexor XR, the only brand-name Effexor currently available on the market.
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Does Cymbalta Cause Side Effects
- major depressive disorder,
- chronic musculoskeletal pain.;
Cymbalta affects neurotransmitters, the chemicals that nerves within the brain make and release in order to communicate with one another. Neurotransmitters either travel across the space between nerves and attach to receptors on the surface of nearby nerves or they attach to receptors on the surface of the nerves that produce them, to be taken up by the nerve and released again .;
Many experts believe that an imbalance among neurotransmitters is the cause of depression as well as other psychiatric disorders. Serotonin and norepinephrine are two neurotransmitters released by nerves in the brain.;
Cymbalta works by preventing the reuptake of serotonin and epinephrine by nerves after they have been released. Since uptake is an important mechanism for removing released neurotransmitters and terminating their actions on adjacent nerves, the reduced uptake caused by Cymbalta increases the effect of serotonin and norepinephrine in the brain.;
The mechanism responsible for its effectiveness treating pain is not known but also is thought to involve its effects on serotonin and norepinephrine in the brain.;
Common side effects of Cymbalta include
Duloxetine And Liver Damage
Among the most well-known Duloxetine side effects is its propensity to cause liver damage. The connection between Cymbalta and liver problems is a significant issue that poses a threat to many patients. The drug can cause fatty liver disease and liver injury. Even low Cymbalta doses can result in liver damage, especially in combination with other medications. The 2011 study included seven patients that were suspected of having Duloxetine hepatotoxicity. It was found that almost all of the patients showed varying extents of liver damage after taking the drug for over two months.
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Common Cymbalta Side Effects
The severity of Duloxetine side effects and for how long they last depend on many individual factors. In an otherwise healthy person who uses Duloxetine for depression disorder treatment, the reactions are generally short-term. Some patients have an increased risk of side effects of Duloxetine than others, depending on their body composition. That aside, there have been some Cymbalta side effects on womens health and sexual adverse reactions. There is discretion advised for Duloxetine and breastfeeding and taking it as a treatment during pregnancy. Expectant mothers and new mothers are advised to discuss using the drug with their medical health professional or the physician in charge of their treatment before taking the first dose.
Common Cymbalta Side Effects Include:
- Discontinuation syndrome and Cymbalta withdrawal symptoms
What Are The Important Side Effects Of Cymbalta
The most common side effects of Cymbalta are
The Cymbalta dosage should be gradually reduced when therapy is discontinued to prevent symptoms of withdrawal.
Anyone considering the use of Cymbalta or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidality, or unusual changes in behavior.
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Does Cymbalta Cause Addiction Or Withdrawal Symptoms
Drug Abuse And Dependence
- In animal studies, duloxetine did not demonstrate barbiturate-like abuse potential.
- While Cymbalta has not been systematically studied in humans for its potential for abuse, there was no indication of drug-seeking behavior in the clinical trials.
- However, it is not possible to predict on the basis of premarketing experience the extent to which a CNS active drug will be misused, diverted, and/or abused once marketed.
- Consequently, physicians should carefully evaluate patients for a history of drug abuse and follow such patients closely, observing them for signs of misuse or abuse of Cymbalta .
How Bad Is Effexor Withdrawal
The dose of Effexor should be slowly tapered to help prevent serious withdrawal symptoms. Abrupt discontinuation of Effexor can lead to symptoms like nausea, dizziness, vomiting, nightmares, irritability, and headaches. Effexor withdrawal symptoms may also include paresthesias, or tingling sensations on the skin.
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