How Should I Use This Medication
Motion sickness, nausea, vomiting, dizziness, and spinning sensation : The usual adult dose of the tablets is 50;mg to 100;mg taken every 4 hours as needed. Do not take more than 400;mg in a 24-hour period. The dose of the long-acting form of dimenhydrinate tablets is 100;mg every 8 to 12 hours, with a maximum of 3 tablets in a 24-hour period. The usual adult dose of dimenhydrinate suppository is 50;mg to 100;mg every 6 to 8 hours as needed.
If you are taking dimenhydrinate for motion sickness, the first dose should be taken at least 30 minutes and preferably 1 to 2 hours before departure.
Pre-radiation therapy : In adults, 50;mg to 100;mg of dimenhydrinate may be given as a suppository or injection, 30 to 60 minutes before receiving radiation therapy. This dose may be repeated as needed up to a maximum of 400;mg over a 24-hour period.
Surgery: To control nausea and vomiting following surgery in adults, the usual dose is 50;mg to 100;mg taken by mouth or 50;mg of injection into a muscle before surgery. After surgery, similar doses can be used up to a maximum dose of 400;mg in a 24-hour period.
Children:;Follow the dosing instructions provided to you by your doctor or pharmacist or the ones provided with the product being used. This medication should not be used for children or infants under one year old.
It is important to use this medication exactly as recommended by your doctor or pharmacist.
Medications That Interact With Drugs That Control Blood Pressure And Cholesterol Levels
Some medications that control blood pressure and cholesterol, when combined with other medications, can increase the risk of undesirable drug interactions.
Diabetes promotes both the development and adverse impact of cardiovascular disease risk factors and as a consequence, accelerates cardiovascular age. Persons with diabetes generally have a cardiovascular age of 10-15 years in advance of their chronological age.
This key message from the 2018 Clinical Practice Guidelines for Prevention and Management of Diabetes in Canada brings the importance of controlling blood pressure and cholesterol in people with diabetes to the forefront.
Lets examine what blood pressure and cholesterol medications can possibly cause undesirable drug interactions, and what can be done to manage them.
Taking Blood Pressure Drugs At Night May Make Them More Effective
Taking blood pressure medication before bed seems to make it more effective
Medication for high blood pressure is more effective when taken at bedtime than the following morning. Knowing the best time to take such drugs is important, because lowering your blood pressure reduces the chances of developing conditions such as heart attacks and strokes by 45 per cent.
Ramón Hermida at the University of Vigo in Spain and his colleagues randomly split 19,000 men and women with high blood pressure into two groups. The team asked half of the people to take their medication before they went to bed and the other half to take it when they woke up.
Each individual recorded their sleep patterns and had follow-up visits to take their blood pressure and check for any side effects. They were monitored for six years on average.
The team found that those who took their dose at bedtime had lower blood pressure during sleep than those who took it the morning after. These reduced levels were linked to a lower risk of heart conditions:;the total number of heart conditions in the bedtime group was 43 per cent less than the morning group.
Daytime measurements alone arent enough, because they could misrepresent someones actual blood pressure, leading to a misdiagnosis, says Hermida.
Journal reference: European Heart Journal, DOI: 10.1093/eurheartj/ehz754
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Antidepressants Used As Sleeping Pills
The FDA has not approved antidepressants for the treatment of insomnia, nor has their use been proven effective in treating sleeplessness. However, some antidepressants are prescribed off-label due to their sedating effects. As with all depression medication, there is a small but significant risk of suicidal thoughts or worsening of depression, particularly in children and adolescents.
Side Effects Of Sleeping Pills
Blood pressure: Like most medications, sleeping pills can have side effects. According to a study published in the journal Geriatrics & Gerontology International, regularly using sleeping pills is linked to increased use of blood pressure medications over time. The researchers who studied 752 older adults with hypertension said the link was observed regardless of their diet, physical activity, body mass index, sleep duration and quality, and blood pressure control.
Lung problems: Sleeping pills can interfere with normal breathing and can be perilous for people with lung conditions, including asthma and chronic obstructive pulmonary disease .
Drug interactions: Sleeping pills can interact with certain medications like painkillers and other sedatives, which may worsen the side effects and turn dangerous.
Drug dependence: One common side effects of sleeping pills is that you may develop the habit of relying on these pills to fall asleep easier or stay asleep longer. The fact is that prescription pills, in particular, are very additive making it difficult for you to stop taking them.
Withdrawal symptoms: People may have withdrawal symptoms like nausea, shaking, and sweating once they stop taking the pills.
Other common side effects of prescription pills may include
- Changes in appetite
- Dizziness or drowsiness during the day
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How Does This Medication Work What Will It Do For Me
Dimenhydrinate belongs to a group of medications called antiemetics. This medication is used to prevent and treat motion sickness as well as nausea and vomiting associated with various conditions such as chemotherapy, radiation, and surgery. It is also used to treat nausea and spinning sensations due to Ménière’s disease and other conditions that cause these symptoms.
Dimenhydrinate works to relieve or prevent nausea and vomiting by affecting the vomiting centre in the brain. Most people can expect some relief of nausea and vomiting within one hour of taking any form of dimenhydrinate. It works to relieve vertigo by affecting the brain and the inner ear.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
Exercise Is A Powerful Sleep Aid
Studies have shown that exercise during the day can improve sleep at night. When we exercise, we experience a significant rise in body temperature, followed a few hours later by a significant drop. This drop in body temperature makes it easier for us to fall and stay asleep. The best time to exercise is late afternoon or early evening, rather than just before bed. Aim for at least 30 minutes four times a week. Aerobic exercises are the best to combat insomnia as they increase the amount of oxygen that reaches the blood.
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Health Effects Of Long
Americans experience a lot of sleepless nights. An unprecedented 50-70 million Americans have sleep problems according to estimates. Insomnia is the most common sleep disorder and the CDC says that more than one third of the country regularly gets less than the recommended amount of rest. With so many people struggling to get enough sleep, sleeping pills have become increasingly popular.
Prescription and over-the-counter sleep aids are meant to be used occasionally, but people are depending on them more and more for nightly relaxation. Medical experts are concerned with this trend because of the negative long-term health effects of these drugs.
What Should I Do If I Experience Side Effects
If you notice severe or dangerous side effects, consult your doctor immediately.
If you notice more mild side effects, you should still speak to your doctor as soon as possible. They may be able to suggest a lower dose, a different medication, or a plan for slowly weaning off the medication.
Know that rebound insomnia can occur when you stop using prescription sleep aids, especially if you stop cold-turkey. It can also happen as youre gradually lowering your dosage. Rebound insomnia can feel even more frustrating than your original insomnia, as you may experience vivid dreams, nightmares, and anxiety. If you experience this, talk to your doctor. They may suggest lowering your dose more gradually.
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As Per A New Study Using Sleeping Pills On A Regular Basis Can Impact Blood Pressure In Older Adults Here Are Some Side Effects And Health Risks Associated With Prescription Pills
New Delhi: Recent surveys have shown that about 90 per cent of Indians are sleep-deprived, increasing the risk of several chronic diseases. Perhaps, you may be one of them and if youre considering taking sleeping pills to get much-needed rest, you would want to read this first. Sleeping pills can be effective when it comes to ending your sleep problems in the short term, however, they can have serious side effects which may vary depending on the types of drug, dosage, etc. As per a new study, using sleeping pills on a regular basis can impact blood pressure in older adults.
Sleeping pills may be sedatives or hypnotics and come in different forms. People can also opt for natural, prescription, or over-the-counter pills. Here are some side effects and risk of using sleeping pills.
The Risky Business Of Sleep Drugs
The risks of sleeping drugs are magnified when the medications are misused. For example, combining sleeping pills with other sedatives, prescription pain drugs, or even alcohol puts you at real risk for serious side effects such as dangerously slow breathing and mental and physical impairment that may linger into the next day, Sateia says.
Buysse says that people should take warnings to use sleeping pills only as directed seriously. For example, most sleep drugs caution that you shouldnt take them unless you can spend 7 or 8 hours in bed.
I especially worry about people who take a sleep medication with 4 hours or less available to them to sleep, he says. After 4 or 5 hours, you can still have the drug circulating in your blood, so you will be less alert at precisely the time you need to be doing things that require your concentration.
Its the exact same reason that people shouldnt drink and drive, Buysse says. Even if you feel relatively alert, you could still be a danger to yourself and others.
Research backs up that concern. People prescribed sleeping pills are nearly twice as likely to be in a car crash, according to 2015 study in the American Journal of Public Health that looked at the medical and driving records of nearly 410,000 adults. The researchers estimated that people taking sleep drugs were as likely to be in a car crash as those driving with a blood alcohol level over the legal limit.
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What Sleep Conditions Can Hurt My Heart Health
Over time, sleep problems can hurt your heart health.
Sleep apnea;happens when your airway gets blocked repeatedly during sleep, causing you to stop breathing for short amounts of time. Sleep apnea can be caused by certain health problems, such as obesity and heart failure.
Sleep apnea affects how much oxygen your body gets while you sleep and increases the risk for many health problems, including high blood pressure, heart attack, and stroke. It is more common among Blacks, Hispanics, and Native Americans than among whites.7
Insomnia;refers to trouble falling sleep, staying asleep, or both. As many as 1 in 2 adults experiences short-term insomnia at some point, and 1 in 10 may have long-lasting insomnia.8;Insomnia is linked to high blood pressure and heart disease. Over time, poor sleep can also lead to unhealthy habits that can hurt your heart, including higher stress levels, less motivation to be physically active, and unhealthy food choices.
For better sleep, get enough natural light, especially earlier in the day. Try going for a morning or lunchtime walk.
What Is The Relationship Between Sleep Apnea And Blood Pressure
Of the two types of sleep apnea, only OSA is linked to high blood pressure. CSA isnt a known cause of hypertension, but it develops in 30 to 50% of people with heart failure.
The prevalence of OSA is estimated to be between 4 and 7% of the general population, but it affects 30 to 40% of people with hypertension. Of people diagnosed with OSA, it is estimated that around half also have high blood pressure.
In healthy individuals, blood pressure naturally lowers by between 10 and 20%; at night, a phenomenon that is sometimes referred to as blood pressure dipping. People with severe OSA experience blood pressure dips of less than 10%, which indicates a nondipping blood pressure pattern.
People who have nondipping blood pressure at night face an increased risk for cardiovascular issues. Additionally, many patients with OSA experience a sudden and pronounced elevation of their blood pressure when they wake up in the morning. This morning surge is another factor that may increase risk for cardiovascular disease. Moderate to severe OSA increases all-cause and cardiovascular mortality.
OSA doesnt only affect blood pressure at night. Studies show that daytime blood pressure levels also increase with sleep apnea severity.
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Benzodiazepine Sedative Hypnotic Sleeping Pills
Benzodiazepines are the oldest class of sleep medications still commonly in use. Benzodiazepines as a group are thought to have a higher risk of dependence than other insomnia sedative hypnotics and are classified as controlled substances. Primarily used to treat anxiety disorders, benzodiazepines that have been approved to treat insomnia include estazolam , flurazepam , quazepam , temazepam , and triazolam .
Drawbacks to benzodiazepine sleeping pills
You can become both physically and psychologically dependent on benzodiazepines. When youre on the pills for a period of time, you may believe that you cant sleep without them, and once you stop taking them, you may actually experience physical withdrawal symptoms like anxiety and rebound insomnia.
Sleeping pills can lose their effectiveness if used on a nightly basis, because the brain receptors become less sensitive to their effects. In as little as three to four weeks, benzodiazepines can become no more effective than a sugar pill.
The overall quality of your sleep can be reduced, with less restorative deep sleep and REM sleep.
You may experience next day cognitive slowing and drowsiness , which may be even worse than the sluggishness you feel from actual sleep deprivation.
Insomnia returns once you stop, even if the medication is effective while taking it. As with the use of all sleeping pills, rather than dealing with your insomnia, youre merely postponing the problem.
Risks And Side Effects Of Sleeping Pills
All prescription sleeping pills have side effects, which vary depending on the specific drug, the dosage, and how long the drug lasts in your system. Common side effects include prolonged drowsiness the next day, headache, muscle aches, constipation, dry mouth, trouble concentrating, dizziness, unsteadiness, and rebound insomnia.
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What Other Drugs Could Interact With This Medication
There may be an interaction between dimenhydrinate and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter , and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 2021. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Gravol
The Truth About Sleep And Blood Pressure
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Youve gone in for your routine physical examination, and youre told what millions of Americans are: you have high blood pressure But, like many Americans, you may not be aware of the truth behind the powerful connection between blood pressure spikes and the quality of your sleep.
As a sleep doctor, I spend a lot of time explaining the health benefits of sleep, from everything like our mental health to even helping us look younger. In short, while quality, restorative sleep helps support our health, the opposite is also true: sleep disorders can affect our mind, bodies and even leave us more prone to depression.
This week Im tackling the most common questions about high blood pressure and sleep, including is lack of sleep can cause high blood pressure; why sleep apnea may play a role, and what might be behind a sudden spike of high blood pressure at night.
Ill finish by giving you tips to lower your blood pressure naturally, no prescription required, and how to more easily fall asleep and fall back asleep if you wake up in the middle of the night; using my Sleep Doctor PM formula. .
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