Wednesday, May 25, 2022
HomeInsomniaDoes Amlodipine Cause Insomnia

Does Amlodipine Cause Insomnia

- Advertisment -

Should You Take Your Blood Pressure Medication At Bedtime

Amlodipine Side Effects | the BEST blood pressure med? Doc’s HONEST opinion!

While it is generally believed that nighttime blood pressure medications are helpful for those with non-dipping blood pressure, this new study seems to indicate that it might be helpful in more effectively lowering blood pressure for a broader range of people.

Dr. Kim Williams, the head of the division of cardiology at Rush University Medical Center and past president of the American College of Cardiology, says he feels itâs too soon to begin recommending that all patients take their medications at bedtime.

âWe need more data from other centers as much of the data favoring this come from a small set of investigators. Other trials and experience are not as strikingly positive,â he noted.

Williams added, âSpeculation would hold that this is a good idea when the patient is known to have nocturnal hypertension but these authors suggest that it works for all comers. We clearly need more data.â

Dr. Satjit Bhusri, assistant professor of cardiology at Zucker School of Medicine at Hofstra/Northwell, also felt that it should not be a blanket recommendation for all patients.

There are many factors to consider, he says, such as:

  • Do you have large swings in your blood pressure?
  • Are you consistent and regular in taking your medication?
  • What other medications are you taking?

Your medication regimen should be personalized for you based upon a discussion with your physician, says Bhusri.

Medication Can Be A Culprit In Insomnia

  • Copy Link URLCopied!
  • Print

Question: I have high blood pressure, high cholesterol and some other health problems. I am wondering if any of my medicines can cause insomnia. If I dont take a sleeping pill, I wake up after two or three hours and cant get back to sleep. I dont feel safe driving 40 miles to work on so little sleep. If one of my prescriptions is causing the problem, I would like to discuss it with my doctor.

Answer: Many medications can interfere with normal sleep. Antidepressants such as Zoloft, Prozac and Paxil are notorious for this reaction. Other medications that you are taking occasionally contribute to insomnia. They include Celebrex, Zebeta, Pravachol and Norvasc.

Inadequate sleep can interfere with driving ability as much as excess alcohol. It can also affect the immune system and memory.

Q: I have been a widow for 10 years and am terribly annoyed by sexual needs I cannot satisfy. I am too embarrassed to talk to my doctor about this. I know it sounds ridiculous, but I am desperate for something to take away my desires.

A: Even though it is difficult, please find a physician with whom you can discuss this personal issue. Some doctors prescribe antidepressants such as Prozac to reduce libido or sexual obsessions. Such drugs have side effects, however, and should not be taken casually.

We dont know whether adding gin-soaked raisins to other natural arthritis remedies would enhance effectiveness, but we cant think of any serious hazards.

Warnings For People With Certain Health Conditions

For people with liver problems: Amlodipine is processed by your liver. If your liver isnt working well, more of this drug may stay in your body longer. This puts you at risk for more side effects. If you have severe liver problems, your doctor may lower your dosage.

For people with heart problems: If you have heart problems, such as narrowing of your arteries, this drug may increase your risk of health problems. You may have low blood pressure, worse chest pain, or a heart attack after starting treatment with this drug, or increasing your dosage. If you have these symptoms, call your doctor or go to the emergency room right away.

Don’t Miss: Garmin Not Tracking Sleep

What Drugs Interact With Norvasc

Impact Of Other Drugs On Amlodipine

CYP3A Inhibitors

Co-administration with CYP3A inhibitors results in increased systemic exposure to amlodipine and may require dose reduction. Monitor for symptoms of hypotension and edema when amlodipine is co-administered with CYP3A inhibitors to determine the need for dose adjustment.

CYP3A Inducers

No information is available on the quantitative effectsof CYP3A inducers on amlodipine. Blood pressure should be closely monitoredwhen amlodipine is co-administered with CYP3A inducers.


Monitor for hypotension when sildenafil is co-administered with amlodipine.

Impact Of Amlodipine On Other Drugs


Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily.


Amlodipine may increase the systemic exposure of cyclosporine or tacrolimuswhen co-administered. Frequent monitoring of trough blood levels of cyclosporine and tacrolimus is recommended and adjust the dose when appropriate.

Nasal Decongestants Or Oral Decongestants

What type of drug is carvedilol , what type of drug is ...

Decongestants can come in handy when youre suffering from a stuffy nose. They can be taken as a nasal spray, like , or as an oral decongestant, like . But one downside is that decongestants can cause insomnia.

If youre using a decongestant, its probably just for a short period of time, so you may decide to push through the nighttime annoyance until you dont need it anymore. You could also consider an alternative, drug-free option like a saline nasal spray or an antihistamine nasal spray like .

Don’t Miss: Va Rating Asthma

What Should I Do If I Experience Side Effects

If you notice severe or dangerous side effects, consult your doctor immediately.

If you notice more mild side effects, you should still speak to your doctor as soon as possible. They may be able to suggest a lower dose, a different medication, or a plan for slowly weaning off the medication.

Know that rebound insomnia can occur when you stop using prescription sleep aids, especially if you stop cold-turkey. It can also happen as youre gradually lowering your dosage. Rebound insomnia can feel even more frustrating than your original insomnia, as you may experience vivid dreams, nightmares, and anxiety. If you experience this, talk to your doctor. They may suggest lowering your dose more gradually.

Is Your Medication Making You Lose Sleep

Certain medications can upset your normal sleep patterns. Switching medications or lowering doses under your doctor’s supervision can often fix the problem.

If you rely on medications for a chronic condition or even minor ailments, you may find yourself sleep-deprived or battling daytime drowsiness.

Certain heart, blood pressure, and asthma drugs, as well as over-the-counter medicines for colds, allergies, and headaches, can interrupt normal sleep patterns, says James Wellman, MD, medical director of the Sleep Disorders Center of Georgia in Augusta.

In fact, a number of common medications can prevent you from falling asleep or staying asleep others can make you groggy or sleepy during the day. Chemicals work differently on everyone, so a given medication may not affect you and your best friend the same way, but the following drugs could cause sleep problems for most people.

Recommended Reading: Samsung Gear S2 Sleep Monitor

Side Effects Not Requiring Immediate Medical Attention

Some side effects of amlodipine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • lack or loss of strength
  • muscle cramps
  • redness of the face, neck, arms, and occasionally, upper chest
  • sleepiness or unusual drowsiness
  • stomach discomfort, upset, or pain


Applies to amlodipine: oral suspension, oral tablet, oral tablet disintegrating

How Can I Sleep Better Without Sleeping Pills

Does anxiety cause insomnia?

Cognitive behavioral therapy is an effective tool for improving sleep and curing insomnia. Behavioral changes often improve sleep without the need for medications.

You may want to:

  • Avoid large meals and alcohol before bed.
  • Cut back on caffeine, including coffee, sodas and chocolate, throughout the day and especially before bedtime.
  • Relax with soothing music, a good book or meditation.
  • Shut off electronic devices at least 30 minutes before bedtime.
  • Stay physically active during the day. Try to get outside, if possible.
  • Stick to a sleep schedule even on weekends.
  • Turn your bedroom into a dark, quiet and cool sanctuary.

Read Also: Service Connected Sleep Apnea Secondary To Ptsd

Norvasc Side Effects List For Healthcare Professionals

Clinical Trials Experience

  • Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
  • Norvasc has been evaluated for safety in more than 11,000 patients in U.S. and foreign clinical trials.
  • In general, treatment with Norvasc was well-tolerated at doses up to 10 mg daily. Most adverse reactions reported during therapy with Norvasc were of mild or moderate severity.
  • In controlled reactions reported during therapy with Norvasc were of mild or moderate severity.
  • In controlled clinical trials directly comparing Norvasc at doses up to 10 mg to placebo , discontinuation of Norvasc because of adverse reactions was required in only about 1.5% of patients and was not significantly different from placebo .
  • The most commonly reported side effects more frequent than placebo are reflected in the table below. The incidence of side effects that occurred in a dose related manner are as follows:

In the CAMELOT and PREVENT studies, the adverse event profile was similar to that reported previously , with the most common adverse event being peripheral edema.

Postmarketing Experience

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Why Taking Blood Pressure Meds At Bedtime May Be More Effective

  • New research suggests that taking your blood pressure medication at bedtime may more effectively reduce your risk of illness or death due to heart and blood vessel disease.
  • Timing of medication is important because blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.
  • Rather than taking a blanket approach, experts say any medication regimen should be personalized for you based on a discussion with your physician.

Should you be taking your blood pressure medication at bedtime rather than in the morning?

Research published in the October 22, 2019, issue of the European Heart Journal suggests that maybe you should.

In the study, the researchers followed 19,084 patients with high blood pressure for a median of 6 years.

The patients were randomly assigned to one of two groups: those who took their blood pressure medication in the morning and those who took it at bedtime.

The researchers found that bedtime medication seemed to make a difference for patients as they had better nighttime blood pressure.

They also had less risk of illness or death due to heart and blood vessel disease.

Recommended Reading: Va Sleep Disorder Rating

What Are The Potential Risks Or Complications Of Sleeping Pills

When you take sleeping medicines night after night, your body may start to depend on them. When you stop the medicine, your insomnia may come back worse than before. This effect is called rebound insomnia.

If youve used sleep aids for a long time, talk to your healthcare provider about how to stop safely. It may take months to stop taking the pills.

You also shouldnt mix sleep aids with other sedatives or alcohol. Theres a possibility of overdosing.

Are Sleeping Pills Safe For Children

Use of amlodipine besylate with AMEX

Some parents give over-the-counter antihistamine medications to children to help them sleep. These medicines arent approved for sleep purposes. Theres a risk of overdosing a child.

Dont give a child supplements like melatonin. Theres no research on their safety in children.

Currently, there are no prescription sleep medicines available for children. Changing a childs sleep behaviors is often the best way to improve sleep.

Don’t Miss: Why Doesn T Apple Watch Track Sleep

Warnings For Other Groups

For pregnant women: Research in animals has shown negative effects to the fetus when the mother takes amlodipine. However, there havent been enough studies done in humans to be certain how the drug might affect a human pregnancy.

Tell your doctor if youre pregnant or plan to become pregnant. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk.

For women who are breastfeeding: Some research has shown that amlodipine passes into breast milk. However, its not known if amlodipine can cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: As you age, your body may not process this drug as well as it once could. More of this drug may stay in your body longer. This puts you at risk for more side effects.

For children: This drug shouldnt be used in children younger than 6 years.

All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

  • your age
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Sleeplessness & High Blood Pressure

If you are experiencing occasional sleeplessness and have high blood pressure or are taking medication to help manage high blood pressure, you may be wondering which over-the-counter nighttime sleep aid options may be right for you. TYLENOL® PM and SIMPLY SLEEP® both contain the active ingredient diphenhydramine. Read more about diphenhydramine and high blood pressure below. to buy a TYLENOL® PM product.

You May Like: Is Your Oxygen Level Lower When You Wake Up

Can I Take Tylenol Products With Diphenhydramine Sleep Aid If I Have High Blood Pressure

If you have high blood pressure and are experiencing pain and sleeplessness TYLENOL® PM may be an appropriate pain reliever/nighttime sleep aid option for you. SIMPLY SLEEP® may also be an appropriate nighttime sleep aid for those with high blood pressure who experience occasional sleeplessness without pain.

How To Take Your Medicine And Get Some Sleep

Insomnia: Symptoms, causes, prevention and cure

Discuss your sleep problems with your doctor, health care practitioner, or pharmacist. There may be other medications that can treat your ailment or health condition without disrupting sleep. Switching medications or lowering dosages with your doctors guidance may help ease insomnia thats due to medication side effects. Likewise, changing the time of day at which you take your medication may help. Restful sleep is important for feeling well and recovering from health problems, so dont lose sleep over medication side effects. Changing your medication could be the perfect prescription for a good nights sleep.

You May Like: Which Of The Following Statements About Sleep-wake Cycles Is False

Does Norvasc Cause Side Effects

Norvasc is a calcium channel blocker used to treat and prevent angina resulting from coronary spasm as well as from exertion. Norvasc is also used to treat high blood pressure .

Chest pain or heartpain occurs because of insufficient oxygen delivered to the heart muscles. Insufficient oxygen may be a result of coronary artery blockage or spasm, or because of exertion which increases the need of the heart for oxygen in patients with coronary artery narrowing .

Common side effects of Norvasc include:

More serious side effects include:

  • increase in the frequency and severity of angina,
  • congestive heart failure.

Increase in the frequency and severity of angina or heart attack due to amlodipine happens on rare occasions in patients with severe coronary artery disease when first starting amlodipine, or at the time of an increase in dosage.

Excessive lowering of blood pressure during initiation of amlodipine treatment can occur, especially in patients already taking other medications that lower blood pressure.

In rare instances, congestive heart failure has been associated with amlodipine, particularly in patients already taking a beta blocker.

Can Norvasc Cause Sleeplessness


. Just so, can amlodipine cause sleeplessness?

The more common side effects that can occur with amlodipine include: swelling of your legs or ankles. tiredness or extreme sleepiness.

Similarly, can blood pressure meds cause insomnia? Heart medications.Anti-arrhythmic drugs used to treat heart rhythm problems can cause insomnia and other sleep difficulties. Beta blockers, used for high blood pressure, arrhythmias, and angina, increase the chance of insomnia, awakenings at night, and nightmares.

Regarding this, can amlodipine cause muscle cramps?

This drug may cause muscle pain, tenderness, or weakness. Sometimes, a very bad muscle problem may happen that may lead to kidney problems. Call your doctor right away if you have muscle signs that last after your doctor has told you to stop taking this drug.

Is Norvasc recalled?

Teva Pharmaceuticals has issued a voluntary recall of its amlodipine/valsartan combination tablets and amlodipine/valsartan/hydrochlorothiazide combination tablets, both used to treat high blood pressure, according to the FDA. The FDA announced the recall on its website Tuesday.

Also Check: Sleep Apnea Va Claim Denied

What Else Can You Do To Better Control Your Blood Pressure

Bhusri feels the key to controlling your blood pressure is your routine.

If your routine helps you take your medications regularly and consistently, then they will be more effective in controlling your blood pressure.

âIt is well known that meds that are prescribed to take at night have a higher rate of consistency,â said Bhusri. âThat is, fewer medicines are forgotten, and a more regular steady state of the medicine is in the patientâs system.

âWorse than persistent elevated pressure,â added Bhusri, âis labile high blood pressure. That is, swings in blood pressure for not adhering to the regimen.â

Bhusri believes that better compliance may have been the reason that the patients in the study had better blood pressure control.

However, Williams adds further advice, saying, âThe main message of our blood pressure therapy in our recent American College of Cardiology hypertension guidelines is to adopt lifestyle changes so that you donât need blood pressure therapy.

Among their recommendations, says Williams, are:

  • Stop smoking.
  • Exercise regularly .
  • Reduce excess weight.
  • Increase potassium.
  • Eat a diet rich in fruits, vegetables, nuts, seeds, and legumes.

Baliga also supports these lifestyle changes, adding to the list good sleep hygiene as well as an assessment for sleep apnea for at-risk patients.

- Advertisment -

Most Popular

- Advertisment -