How Long Do Side Effects Last
The duration of potential side effects associated with Crestor will depend on the type of side effect and how long the medication has been used. Mild side effects usually go away over a short period of time . More severe side effects range from days to permanent:
- Rhabdomyolysis will usually begin to resolve within days of discontinuing the medication
- Autoimmune myopathy is often severe and may persist long after the discontinuation of medication
- Liver problems may be permanent and unfortunately do not usually appear until an individual has been taking Crestor for several months
Letter Urging Ban Of Cholesterol
Lester Crawford, DVM, Acting CommissionerFood and Drug AdministrationRockville, MD 20854
Dear Dr. Crawford,
As you are aware, on March 4th of this year, we petitioned the FDA to ban the recently-marketed cholesterol-lowering drug rosuvastatin because of seven post-marketing cases of life-threatening rhabdomyolysis and nine cases of renal failure or renal insufficiency, both of which problems had also been identified during the pre-approval clinical trials. Of these post-approval cases, one case of rhabdomyolysis occurred in the United States, where the drug had only been on the market for little over five months, as did two cases of kidney toxicity. The other cases of rhabdomyolysis and drug-induced kidney disease occurred in the UK or Canada, where the drug had been on the market for a longer time.
We have now obtained new information from the FDA about many additional post-marketing cases of rhabdomyolysis and kidney toxicity in reports updated to April 13th. In the relatively short interval since our first petition, 11 additional cases of rhabdomyolysis in patients using rosuvastatin, including at least 10 in the United States, have been reported to the FDA, as have three additional cases of renal failure or renal insufficiency in the United States, all in people using 10 milligrams.
According to an alert posted on May 17th on the British governments web site :
What Are Lipitors Side Effects In Males Vs In Females
Lipitors side effects didnt differ between males and females during clinical trials.*
To view some of Lipitors side effects, see the sections above for lists of mild and serious ones. For a full list of side effects that the medication may cause, check out Lipitors patient information.
* Sex and gender exist on spectrums. Use of the terms male and female in this article refers to sex assigned at birth.
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Medications That Can Cause Nightmares
Sleep plays a major role in ones physical and mental health. From boosting your mood and helping with heart health to strengthening immunity and weight management, sleep has major benefits. Most adults need around seven to nine hours each night to get the full range of benefits. Nightmares are one factors that impact your quality of sleep. While nightmares are most often associated with children, adults can definitely experience them. One cause of your nightmares may be your medication. Below are some of the common medications that can cause nightmares.
How Much To Take
How much you take depends on what you’re taking rosuvastatin for:
- preventing heart attacks and strokes – the usual dose for adults is 20mg once a day. Sometimes a lower dose may be prescribed.
- high cholesterol – the usual starting dose for adults and children is 5mg to 10mg once a day. If needed, your doctor may increase your dose every 4 weeks up to 20mg a day.
The maximum dose for children is 20mg a day.
If you have very high cholesterol, you may be prescribed a higher dose of 40mg a day by a specialist. This dosage is not suitable for everyone.
Ask your doctor or pharmacist for advice if you’re unsure how much to take.
Do not reduce your dose without talking to your doctor first.
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Does Lipitor Cause Eye
Its possible, but very rare, that Lipitor could cause eye-related side effects.
If you have blurry vision or eye-related side effects while youre taking Lipitor, talk with your doctor or pharmacist. They can help determine whats causing your symptoms. This could include other medications you take besides Lipitor.
In some cases, your doctor may recommend you stop taking Lipitor and use another drug for your condition.
When You Must Not Use It
Do not use CRESTOR if you are pregnant or intend to become pregnant. Ask your doctor about effective methods of contraception.
If you become pregnant, stop taking CRESTOR as soon as you find out and see your doctor immediately.
Do not use CRESTOR if you are breast feeding. We do not know if your baby can take in CRESTOR from breast milk if you are breast feeding.
Do not use CRESTOR if you have active liver disease or if tests show you have elevated levels of liver enzymes which may show that you have a problem with your liver.
Do not use CRESTOR 40 mg if you have:
- low thyroid hormone levels
- a personal or family history of hereditary muscular disorders
- a previous history of muscular problems from using other lipid-lowering agents
- a history of very heavy alcohol use
- Asian heritage
- been prescribed another class of lipid lowering agent called a fibrate
- been prescribed any medicine containing fusidic acid
- severe kidney impairment
- situations that may increase CRESTOR blood levels
Do not use after the use by date printed on the pack. It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.
Do not use CRESTOR if the packaging is torn or shows signs of tampering.
Do not use it to treat any other complaints unless your doctor tells you to. Do not give this medicine to anyone else.
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Sleepless Maybe It’s Your Statin
3 Min Read
CHICAGO, Nov 7 – A popular drug used to keep cholesterol in check might be interfering with a good nights sleep, U.S. researchers said on Wednesday.
A large study looking at sleep patterns of people who took the statin drug Zocor or simvastatin found they had significantly worse sleep quality compared with people who took Pravachol or pravastatin, another cholesterol-lowering drug.
The findings are significant because sleep problems can affect the quality of life and may have adverse health consequences, such as promoting weight gain and insulin resistance, Dr. Beatrice Golomb, of the University of California at San Diego School of Medicine, said in a statement.
She presented her study at the American Heart Association meeting in Orlando, Florida.
While both simvastatin and pravastatin help lower levels of LDL or low-density lipoprotein, the so-called bad cholesterol, simvastatin is lipophilic, meaning it is soluble in fats, while pravastatin is hydrophilic, meaning it is soluble in water.
Because simvastatin is fat soluble, it can more easily penetrate cell membranes, making its way across the blood-brain barrier, a mechanism that protects the brain from chemicals in the blood.
Golomb wanted to see if this difference explained why some people on statins reported having trouble sleeping.
What Are Fibric Acid Derivatives
Fibrates aim to lower blood triglyceride levels by 35 to 50 percent and raise HDL cholesterol levels by 5 to 20 percent. Fibrates work by reducing the amount of triglycerides produced by the liver, and increasing the rate at which the triglycerides are removed from the bloodstream.
While they can increase HDL cholesterol, fibrates do not work to lower LDL cholesterol and are often combined with statins to accomplish this. Fibrates are also prescribed to help prevent heart attacks in at-risk patients with high blood triglycerides and low HDL cholesterol.
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Does Crestor Make You Gain Weight
Statins increase weight and blood sugar levels and raise the risk of diabetes, a study has found, but experts maintain that the benefits of the drug “greatly outweigh” the risks. Now a study has produced strong evidence that the drugs’ basic mechanism can lead to weight gain and a modest increase in diabetes risk.
Subsequently, question is, what are the bad side effects of Crestor? The most common side effects may include:Headache, muscle aches and pains, abdominal pain, weakness, and nausea. Additional side effects that have been reported with CRESTOR include memory loss and confusion. Tell your doctor if you have any side effect that bothers you or that does not go away.
Also, what foods should be avoided when taking Crestor?
Avoid eating foods high in fat or cholesterol, or rosuvastatin will not be as effective. Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage. Some antacids can make it harder for your body to absorb rosuvastatin.
Is weight loss a side effect of Crestor?
Report any unexplained fatigue, shortness of breath, unexplained cough, weight loss, abdominal pain, dark urine or yellowing of the skin. Crestor should not be taken during pregnancy or while breastfeeding.
Does Crestor Cause Insomnia
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Dosage For Heterozygous High Cholesterol
- Typical dosage: 540 mg once daily.
- Typical dosage: 520 mg once daily.
- Typical dosage: 510 mg once daily.
This medication has not been studied in young children for this purpose. It should not be used in children younger than 8 years.
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This increases your risk of side effects.
Your doctor may start you on a lowered dosage or a different medication schedule. This can help keep levels of this drug from building up too much in your body.
Warning Disclaimer Use For Publication
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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What Is In This Leaflet
This leaflet answers some of the common questions people ask about CRESTOR. It does not contain all the information that is known about CRESTOR.
It does not take the place of talking to your doctor and pharmacist.
All medicines have risks and benefits. Your doctor will have weighed the risks of you taking CRESTOR against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
Crestor Side Effects And How To Avoid Them
Crestor is the brand name for the lipid-lowering medication rosuvastatin calcium. Crestor is part of a class of medications known as statins. Statins are HMG-CoA reductaseinhibitors because they block the activity of the enzyme HMG-CoA in the liver. Individuals taking Crestor should anticipate a reduction in total cholesterol, low-density lipoprotein cholesterol, and triglycerides with a concomitant increase in high-density lipoprotein cholesterol.
Crestor should be used under the care of a healthcare professional and part of a healthy lifestyle which may include diet modification and exercise. In the U.S., Crestor is manufactured by AstraZeneca and is available in 5, 10, 20, or 40 mg tablets.
Lipid-lowering medications like Crestor can be associated with potentially serious adverse effects. In this article, we will discuss some of the side effects, warnings, and interactions associated with Crestor use as well as how to avoid them.
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Should Coq10 Be Taken With Food
CoQ10 is fat soluble, meaning that its stored within fat in your body.
Fat soluble substances are typically best absorbed when consumed alongside food that contains some fat in it.
And finally, be aware that not all forms of CoQ10 are equal. The ubiquinol form of CoQ10 is the most absorbable .
What Should I Avoid While Taking Rosuvastatin
Avoid eating foods high in fat or cholesterol, or rosuvastatin will not be as effective.
Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.
Some antacids can make it harder for your body to absorb rosuvastatin. Avoid taking an antacid that contains aluminum or magnesium within 2 hours after taking rosuvastatin.
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Niacin Nicotinic Acid Vitamin B3
Prescription: Yes and over-the-counter Generic: Yes Preparations: Tablets of 50, 100, 250, 500 and 750 mg. Capsules of 125, 250, 400, 500, 750 and 1000 mg.
Prescribed for: Nicotinic acid is used for treating niacin deficiency and elevated blood cholesterol and/or triglyceride levels and for increasing HDL cholesterol.
Side effects: The most common side effects of nicotinic acid are stomach upset, flushing or redness of skin on the face and neck, headache, itching, dizziness, lightheadedness, diarrhea, and tingling sensations of the extremities. Rare cases of liver failure or muscle injury have occurred from the use of nicotinic acid.
Renal Impairment And Dose Adjustment
Individuals with mild to moderate renal impairment do not require dose adjustment when taking Crestor. However, exposure to rosuvastatin is increased to a clinically significant extent in individuals with severe renal impairment who are not receiving hemodialysis. Crestor dosing should be adjusted for individuals with severe renal impairment.
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Do Lipitors Side Effects Vary Based On Its Strength
Lipitors side effects dont vary based on the strength of the drug. However, some side effects happen more or less often depending on its strength.
For example, in clinical trials, people taking a lower dose such as 10 mg, were more likely to have swelling in their nasal passages and throat. This was compared with people taking the highest dose of 80 mg.
Additionally, joint pain was most commonly reported by people taking a 40-mg dose.
To see a list of how often certain side effects were reported based on the dose of Lipitor people took, view Lipitors patient information.
What Should You Do If Your Medications Are Causing Insomnia
Sleep is important to your health, so insomnia that doesnt go away isnt something to overlook.
If you think your medications are causing insomnia, you should talk to your healthcare provider about it. They may:
Recommend an alternative medication
Recommend a supplement like melatonin to help promote sleep
Prescribe a stronger medication to help you sleep
Types Of Medication Known To Cause Insomnia And Nightmares: Are Prescription Drugs Ruining Your Sleep Pattern
Insomnia can influence every aspect of your life. Studies show that difficulties falling or staying asleep may come to the detriment of memory, attention span, and mental well-being.
Although the condition is generally associated with chronic diseases like diabetes, obesity, and depression, almost everyone will experience spells of sleeplessness at some point in their life. Today, the Center for Disease Control and Prevention estimates that one-quarter of the U.S. population suffer sporadically from inadequate sleep. Without a clear medical cause, its easy to chalk it up to everyday stress however, the culprit could be hiding in your medicine cabinet.
Chronic conditions aside, insomnia is also a side effect of a variety of medication. The following list from the AARP contains some of the most commonly prescribed drugs known to disturb sleep patterns.