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Does Zoloft Cause Insomnia

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Other Ssris And Weight Gain

Sertraline isnt the only antidepressant that can cause weight gain. Many other antidepressants, including other SSRIs, are associated with some degree of weight gain.

In a published in the journal Translational Psychiatry, researchers noted that SSRI users gained an average of 4.6 percent of their body weight over four years of treatment.

Other research has found that certain antidepressants, such as , often cause cravings for carbohydrates and significant weight gain during treatment.

As for specific SSRIs, the data varies. Can cause weight gain? Relatively little, according to one , which found that people with depression who underwent treatment with escitalopram gained an average of just 0.34kg over six months.

Similarly, SNRI antidepressants such as duloxetine can also cause weight gain. In one , researchers noted that leads to a modest amount of weight gain when its used as a long-term treatment for depression.

Put simply, weight gain is a fairly common side effect of both SSRIs and other antidepressants — not an isolated side effect that only occurs with sertraline.

Zoloft Insomnia Final Thoughts

Is your dependence on Zoloft causing insomnia?

There is a strong likelihood that it is.

But what can you do about it?

You probably do not have the luxury to see if it will ever go away, because chronic insomnia is deadly for your health and finances.

Therefore, it is in you and your familys best interest to explore other alternative treatments for depression.

The best Zoloft and insomnia cure is when you can finally wean yourself off of Zoloft.

The Signs Of Insomnia

Insomnia is characterized by a number of symptoms. If a patient has one or more of the symptoms they are considered to have insomnia. These symptoms include

  • non-refreshing sleep
  • waking up often during the night and having trouble going back to sleep
  • difficulty falling asleep and waking up too early in the morning

If a patient begins to experience any of these symptoms while taking Zoloft, they should consult a doctor. There are a number of home remedies that may help patients find relief but some patients stop taking Zoloft to stop the effects of insomnia.

What Should You Do If Your Medications Are Causing Insomnia

Sleep is important to your health, so insomnia that doesnt go away isnt something to overlook.

If you think your medications are causing insomnia, you should talk to your healthcare provider about it. They may: 

  • Recommend an alternative medication
  • Recommend a supplement like melatonin to help promote sleep
  • Prescribe a stronger medication to help you sleep

What Are Zoloft Side Effects

Does Zoloft cause Insomnia?  The Bad Side of Zoloft You ...

Zoloft, that is primarily used to treat depression, OCD, anxiety disorders, PTSD, and other similar conditions can cause several side effects.

Some of these side effects are listed below:

  • Headache
  • Breast pain
  • Back pain

Some of the above-mentioned effects may be caused after the drugs short-term use ,while others may be caused after its long-term use. These are further discussed in detail in the following sections.

Use Of Ssri Antidepressants In Older People

SSRIs are safer than tricyclic antidepressants for older people because they do not disturb heart rhythms and rarely cause dizziness that results in falls. But liver function is less efficient in older people, so there is a greater risk of drug interactions involving the cytochrome P450 system. For that reason, older people do best with rapidly metabolized drugs like sertraline.

Precautions If You Take Trazodone

  • Because trazodone might not work well to treat insomnia after a few weeks, check in with your doctor periodically to discuss how its going or whether its still working.
  • If you have trouble getting to sleep, take it several hours before you go to bed. If you have trouble staying asleep, take it within 30 minutes of bedtime.
  • Avoid trazodone if youre recovering from a heart attack. Inform your doctor if you have abnormal heart rhythms, weakened immunity, an active infection, or liver or kidney disease. Use it cautiously if you have heart disease.
  • Watch for adverse effects. Thats especially important for people older than 55 or so because theyre more susceptible to abnormal heart rhythms and falls caused by dizziness or drowsiness. Close monitoring is also crucial if youre taking trazodone with another antidepressant.
  • As with any sleep medication, never mix trazodone with alcohol, and use it cautiously if youre taking other sedating medications or anti-hypertensive drugs. Ask your doctor or pharmacist about other possible drug interactions.
  • If you develop an erection thats unusually prolonged or occurs without stimulation, discontinue the drug and contact your physician. Also call your doctor if you develop a fever or sore throat, or other signs of infection while taking trazodone.

Additional reporting by Chris Hendel and Ronald Buchheim

Other Ways To Treat Insomnia From Zoloft At Home

Insomnia is one of the more common side effects of antidepressants such as Zoloft. In fact, data from clinical trials shows that 20 percent of people who use Zoloft report at least some degree of insomnia during treatment.

If you find it difficult to fall or stay asleep while using Zoloft, making a few changes to your habits and lifestyle can often help. Try the following techniques to make falling asleep easier while you use Zoloft: 

Why Does Sertraline Cause Weight Gain

While scientists and healthcare providers have long known that antidepressants can cause weight gain, there isnt a huge amount of evidence showing why this happens.

Weight gain occurs when people consume more calories from foods and beverages than theyre able to burn through activity.

A variety of environmental factors can affect calorie intake and activity level, including access to certain types of food, large average portions and a lack of opportunities to exercise.

Medical conditions, such as hypothyroidism, Cushing syndrome and polycystic ovary syndrome , may also contribute to weight gain in certain circumstances.

Currently, there doesnt appear to be any evidence to show that sertraline has a negative effect on your metabolism.

In one study from 2009, researchers found that sertraline did not have any significant impact on thyroid function, limiting any potential metabolic effects.

One is that antidepressants such as sertraline may stimulate your appetite and make you feel hungrier than normal by affecting your ability to suppress the urge to eat.

This means that if you use sertraline or another antidepressant, you may feel less satisfied after you eat food, causing you to eat larger portions and take fewer steps to control your total calorie intake. 

Over time, this increase in calorie intake can lead to weight gain if you dont also increase your activity level. 

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Zoloft:uses And Side Effects

According to the Centers for Medicare & Medicaid Services , Zoloftor its generic name, sertraline is an . It can also be used to treat panic disorder, post-traumatic stress disorder, obsessive-compulsive disorder, and other similar conditions.

Zoloft is considered a selective serotonin reuptake inhibitor,or SSRI. This type of antidepressant functions by affecting the secretions commonly associated with emotion or mood.

Serotonin, norepinephrine, and dopamine are all altered or effective by SSRIs in some way, as stated by the National Institutes of Health. The manipulation of emotions via alteration of brain secretions has always been a tricky path and can lead to several side effects.

For instance, Mayo Clinic reports that several side effects have been linked to Zoloft, as well as other medicines using the generic sertralineincluding irritability, reduced libido, inability to complete intercourse aggressive tendencies, sleep difficulty, and confusion.

Many of these side effects are to be expected, but anything that impacts sleep needs to be carefully considered. Sleep difficulties and insomnia can have have a serious effect on your day to day functioning and quality of life.

What Are The Side Effects Of Sertraline

You may experience side effects when taking sertraline. These include:

  • Headache
  • Decreased appetite or weight loss
  • Unusual drowsiness
  • Decreased sexual ability or desire

Less common side effects include fever, racing heartbeat, nosebleeds, or sudden loss of consciousness.

Although many side effects may go away with time, if you experience side effects while taking sertraline, let your doctor know. They may suggest a dosage change, a change from sertraline to another medication, or an additional medication to address the side effect.

Zoloft Dependence And Addiction

Does Zoloft cause Insomnia?  The Bad Side of Zoloft You ...

Since Zoloft is a long-term medication, there is no inherent danger in taking it for months or even years. However, since its a mind-altering drug, it can cause . When a person becomes unable to feel normal or get through the day without taking Zoloft, theyve become dependent on the medication. There is a debate about whether Zoloft is actually addictive because there is no evidence that people who take Zoloft ever have cravings for it. Nevertheless, people who stop taking Zoloft can experience withdrawal.

To avoid withdrawal, some people may continue to use Zoloft even though they believe they no longer need it. In some cases, they might doctor shop for more Zoloft prescriptions or buy the medication illegally, all to keep away withdrawal symptoms. This cycle of withdrawal and relapse is characteristic of an addiction disorder. Fortunately, addiction to any prescription drug can be cured with medically-supervised and therapy at a rehab facility.

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The Bottom Line On Trazodone

For the average person who has occasional bouts of insomnia, making certain lifestyle changes may help the most, including avoiding big meals, alcohol, smoking, and exercising late at night, and working or watching TV in bed.

If these actions dont help, you could consider, with your doctors input, trying an inexpensive over-the-counter drug containing an antihistamine, such as diphenhydramine or for just a few nights.

But its important to know that though those drugs are FDA-approved to treat insomnia, the American Academy of Sleep Medicine doesnt recommend them. In addition, drugs such as diphenhydramine can cause dependence when taken for longer than directed , and they have other risks, such as constipation, confusion, , and next-day drowsiness.

If your insomnia lasts longer than a few nights, see your doctor to determine whether other factors, such as pain, heartburn, hot flashes, and drug side effects, could be disturbing your sleep. If these are ruled outor if your insomnia persists despite treatment of the underlying problemsyou can try nondrug sleep treatments, such as cognitive behavioral therapy, which appear to yield better and more lasting results than any sleep medications. The AASM recommends CBT before resorting to medication.

If your doctor recommends sleeping pills for more than a temporary bout of insomnia without mentioning nondrug therapy, ask about these options yourself. For more on such treatment, see our latest tips on how to treat insomnia.

Patients At Risk Of Discontinuation

Patients may be tempted to discontinue their antidepressant medication after they begin to feel better, a practice that invites both early relapse of illness and antidepressant discontinuation syndrome. Women may discontinue antidepressant use after discovering that they are pregnant. Ideally, patients should be counseled regarding the risks of illness relapse, the importance of treating symptoms to remission, the need for continuation and maintenance pharmacotherapy, and the need for gradual discontinuation of medications before discontinuing care.,

Does Zoloft Cause Insomnia

Zoloft is an antidepressant, which is used for the treatment of a number of disorders/issues, ranging from OCD to panic disorder and major depressive disorder. While Zoloft is indeed a rather efficient solution for such problems, it like all medications comes with a number of side effects, one of which is .

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First introduced in 1991 by Pfizer, Zoloft is nowadays a generic medication, a months worth of which costs only some $1.50. With that in mind, it is hardly surprising that it has grown into the second most often prescribed antidepressant and psychiatric medication in the US.

While the benefic effects of medications are supposed to outweigh their side-effects , with the Zoloft-insomnia link, the side effect defeats the very purpose of the pill, making suffering worse for some patients, instead of better.

If you are an insomnia-sufferer on account of Zoloft, or just someone prescribed Zoloft for the first time, you will want to know:

  • What are the odds that Zoloft will trigger insomnia problems in users?
  • Why and how does Zoloft cause insomnia ?
  • How can you deal with Zoloft-induced insomnia?
  • How long is this insomnia problem likely to last?
  • Should you arbitrarily stop using Zoloft?
  • Let us try to answer these questions, one step at a time.

    6The bottom line

    The Effects Of Antidepressants On Sleep

    Nicholas Demartinis, MDPsychiatric Times

    Knowledge of how different antidepressants are likely to affect parameters of sleep can provide an important basis for selecting an appropriate antidepressant drug among the roughly 2 dozen marketed options to meet the needs of depressed patients.

    Many psychiatric disorders are accompanied by disturbance of sleep. In addition to resolving sleep-related symptoms through their primary therapeutic effects, many psychiatric medications have secondary effects on sleep that can contribute to their overall therapeutic benefit or sometimes counter them through adverse effects. The antidepressants are a prototypical example of the potentially complex interactions between psychiatric medications and sleep.

    It is thought that all approved antidepressants work through modulation of monoamine neurotransmitters, including norepinephrine, dopamine, and serotonin, all of which have been shown to exert prominent effects in regulating sleep-wakefulness and sleep architecture .1 In particular, norepinephrine and serotonin play prominent roles in suppressing REM sleep, while acetylcholine plays a key role in the initiation of REM sleep.2 A number of antidepressants affect other neurotransmitter receptors, such as muscarinic ACh, α1-adrenergic, and histamine H1receptors, that are implicated in sleep regulation.3



    Antidepressants and their effects on sleep physiology



    Selective SNRIs

    Atypical antidepressants

    Large Percentage Of Zoloft Users Experience Insomnia

    Zoloft is prescribed for the treatment of depression, obsessive compulsive disorder , social anxiety disorder, and premenstrual dysphoric disorders . Studies have demonstrated a link between zoloft and insomnia with about a third of users experiencing symptoms. This was more pronounced among patients being treated for OCD, but less for women being treated for .

    Let’s take a look at some of the issues facing Zoloft users.

    • What Is The Connection Between Zoloft And Insomnia?
    • How Can I Deal With Insomnia Caused By Zoloft?
    • How Long Will The Insomnia Caused by Zoloft Last?

    Zoloft Side Effects To Expect In The First Week

    During your first week of taking Zoloft you may experience some initial side effects even if youre taking the medication exactly as prescribed by your doctor. This happens because it takes time for the body to become used to the medication. Some of the most common side effects that people have during their first week of taking Zoloft include:

    • Headache
    • Loss of appetite
    • Increased sweating

    Taking Zoloft may make you feel uncomfortable or weird at first as your body starts to process the medication. After a week or two these side effects will go away for most people as their bodies get used to the medication. Its possible to experience some of these side effects sporadically throughout the duration that youre taking Zoloft, especially if your doctor increases your dose. 

    Although its rare, Zoloft can cause more serious side effects like: 

    • Unusual weight loss 
    • An increased risk of bleeding 
    • Eye pain that indicates angle-closure glaucoma 
    • Sexual dysfunction such as delayed ejaculation 
    • Manic episodes for people with undiagnosed bipolar disorder
    • Allergic reactions  
    • Seizures 

    Zoloft also comes with a box warning for suicidal thoughts and behaviors. Short-term studies have shown that antidepressants increased the risk of suicidality in children, adolescents, and young adults when compared to a placebo.If youre taking Zoloft and start to have extreme mood changes and/or suicidal thoughts or behaviors, you should seek medical advice right away.  

    How Quickly Can You Expect Such An Effect To Come Into Play

    It usually takes a few weeks for these insomnia-related symptoms to ebb away, into a more manageable form. The problem never really goes away, but its severity diminishes noticeably.

    The bad news is, that for some people, this effect of natural alleviation never comes about their symptoms remain as unbearable as they are on day one, throughout the Zoloft treatment.

    Insomnia Causes Cures And Treatments

    Does Zoloft cause Insomnia?  The Bad Side of Zoloft You ...

    Do you struggle for hours to get to sleep, no matter how tired you are?

    Or do you wake up in the middle of the night and lie awake for hours, anxiously watching the clock?

    If so, youre in good company.

    Insomnia is a very common sleep problem.

    Its frustrating to toss and turn during the night, only to wake up bleary-eyed at the sound of the alarm and drag through the day exhausted.

    Insomnia takes a toll on your energy, mood, and ability to function during the day.

    Chronic insomnia can even contribute to health problems such as heart disease, high blood pressure, and .

    But you dont have to put up with insomnia.

    Simple changes to your lifestyle and daily habits can put a stop to sleepless nights.

    Definition of Insomnia

    Insomnia is the inability to get the amount of sleep you need to wake up feeling rested and refreshed.

    Because different people need different amounts of sleep, insomnia is defined by the quality of your sleep and how you feel after sleepingnot the number of hours you sleep or how quickly you doze off.

    Even if youre spending eight hours a night in bed, if you feel drowsy and fatigued during the day, you may be experiencing insomnia.

    Although insomnia is the most common sleep complaint, it is not a single sleep disorder.

    Its more accurate to think of insomnia as a symptom of another problem.

    The problem causing insomnia differs from person to person.

    Best Insomnia Therapy, Pure Relaxation Music for Sleeping, Healing Music for Deep Sleep, Sleep Music

    Home Remedies For Insomnia

    Insomnia can be combated in many ways, such as a regular sleep-wake cycle.

    • Patients with insomnia should try to go to bed and wake up at the same time every day.
    • Patients shouldnt exercise within the two hours before bedtime.
    • Napping after three in the afternoon should also be avoided.
    • Caffeine, alcohol and nicotine should be avoided in the four to six hours before bedtime.
    • Large meals should be eaten more than two hours before bedtime.
    • Winding down can also help patients rest peacefully.
    • Soft music or reading can help patients rest.
    • If sleep escapes a patient after twenty minutes of trying to fall asleep, they should do a quiet activity somewhere else and then return to bed when sleepy.

    Fainting And Extreme Dizziness

    According to the FDA, fainting is not frequently reported, but is still a potential side effect of sertraline. 

    A small percentage of people who use sertraline may also experience severe dizziness and lightheadedness. 

    If you feel faint, weak or severely dizzy, or feel differences in your heart rate after taking sertraline, you should seek medical help as soon as possible.

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    • About

    Nathan Yerby is a writer and researcher. He is a graduate of the University of Central Florida.

    • Connell, P. . SSRI Withdrawal Symptoms. Retrieved on July 22, 2019, from
    • . Zoloft. Retrieved on July 19, 2019, from
    • Guzman, F. . Antidepressant Discontinuation Syndrome: Diagnosis, Prevention and Management. Psychopharmacology Institute. Retrieved on July 23, 2019, from
    • MedlinePlus. . Sertraline. U.S. National Library of Medicine. Retrieved on July 19, 2019, from
    • National Alliance on Mental Illness. . Sertraline . Retrieved on July 19, 2019, from
    • Pietrangelo, A. . Prozac vs. Zoloft: Uses and More. Retrieved on July 19, 2019, from
    • Purse, M. . Precautions You Should Take Before Taking Zoloft. Retrieved on July 19, 2019, from
    • RxList. . Zoloft. Retrieved on July 19, 2019, from
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    • WedMD. . Zoloft. Retrieved on July 19, 2019, from

    Clinically Reviewed:

    David Hampton

    • About

    All of the information on this page has been reviewed and verified by a certified addiction professional.

    Effects On Antidepressants On Sleep

    It is well known that some classes of antidepressant drugs may deteriorate sleep quality mainly due to activation of serotonergic 5-HT2 receptors and increased noradrenergic and dopaminergic neurotransmission .2). Among them, most prominent are serotonin and norepinephrine reuptake inhibitors , norepinephrine reuptake inhibitors , monoamine oxidase inhibitors , selective serotonin reuptake inhibitors , and activating tricyclic antidepressants .

    Antidepressant Insomnia Is The Cure Worse Than The Cause

    Antidepressant insomnia is a common side effect of medication taken to help a non-sleep-related condition such as depression, anxiety, chronic fatigue syndrome, fibromyalgia or another of the many conditions for which antidepressants are sometimes prescribed.

    Antidepressant medications are well-known for causing insomnia as a side effect. The SSRIs seem to be the main culprits in this particular side effect, but any antidepressant may cause insomnia in those who are already susceptible to it.

    Sertraline And Insomnia Does It Ever Go Away

    Anyone at all on here that has taken Zoloft and has insomnia, does the insomnia EVER go away? From what I have read on iodine, this antidepressant is one that is guaranteed to cause insomnia long term while taking it. What’s the point of taking the medicine to get better if you’re miserable without sleep? Someone please chime in and give me some hope cuz I can’t live life this or keep taking sleeping medicine because of another medicine side effects. and insomnia don’t mix well

    0 likes, 20 replies

    Learn More About Sertraline

    While many of the side effects listed above can look alarming, its worth remembering that most people who use sertraline either experience no side effects at all, or light, transient side effects that disappear as they become accustomed to the medication. 

    You should not take sertraline if you have glaucoma, history of heart problems, or are breastfeeding.

    For the vast majority of users, its a safe, effective and important medication that provides real benefits.

    However, in addition to the side effects listed above, sertraline can potentially have drug with a wide range of other medications and substances, like combining alcohol and sertraline, monoamine oxidase inhibitors , nonsteroidal anti-inflammatory drugs such as ibuprofen, or even St. John’s Wort.

    Use of sertraline with other SSRIs could lead to an increased risk of a life-threatening condition called serotonin syndrome. Our Sertraline 101 Guide goes into more detail on sertraline interactions. 

    Be sure to discuss all drugs you are taking, including over-the-counter medicine, with your healthcare professional before taking sertraline.

    Do not stop taking sertraline without seeking medical advice. 

    Abruptly sertraline before your next dose could lead to serious withdrawal symptoms, including eye pain, nausea, headaches, irritability, nightmares, or suicidal thoughts.

    Trazodone Risks You Should Know About

    Does Zoloft Cause Insomnia

    Trazodone isnt without risks, however. It appears to be more likely than other sleep drugs to leave you feeling , which increases the chance of having an accident, particularly while driving or using heavy machinery.

    It can also cause abnormally low blood pressure and, in turn, trigger dizziness or even fainting, particularly in seniors, which can increase the risk of falling. A in the Canadian Medical Association Journal found that seniors with dementia who were given trazodone as a sleep aid were as likely to fall as seniors given antipsychotics, other drugs that can cause sedation.

    Trazodone can also cause heart rhythm disorders. And some evidence suggests that it can cause priapism, or persistent erection, a medical emergency that may require surgery and can lead to impotence if not treated promptly.

    And a black box warning in the package insert notes that trazodone, like other antidepressants, can increase the risk of suicidal thoughts and behavior in children and adolescents, even when taken at approved doses for depression.

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