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What Medications Aggravate Restless Leg Syndrome

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Restless Leg Syndrome Treatment: Women Heart Disease And Stroke

Studies are showing that ongoing restless leg syndrome treatment may be essential for maintaining good heart and brain health.

And this restless leg syndrome treatment appears to be especially true for middle aged women.

The reason is because evidence is showing a link between symptoms of restless legs syndrome , heart disease, stroke, and high blood pressure .

Heart disease is the leading cause of death in the United States, with almost 600,000 deaths per year. Strokes account for about 130,000 yearly deaths.

Hypertension, known as the “silent killer” because it often goes undetected, is a major risk factor for heart attack and stroke. In fact, estimates are that as many as 17 million Americans have elevated blood pressure and don’t even know it.

Does Cbd Work For Restless Leg Syndrome

Are you are having trouble sleeping at night because of unpleasant sensations in your legs?  Jerking or twitching movements during sleep are signs of restless leg syndrome. Because of sleep disturbances at night, you struggle to stay awake during the day and feel generally tired.

Even though restless leg syndrome has no cure, medications can treat its symptoms. And people with RLS who have used CBD products claim that they experienced relief from the symptoms. They were able to sleep peacefully at night and have robust mental health. Cannabidiol is a chemical component of the cannabis plant that users allege to have potential benefits. Studies are still being conducted to prove these claims.

Causes Of Restless Leg Syndrome

Scientists are yet to learn the cause of restless leg syndrome. However, genes play a significant role according to this study conducted by the University of Extramadura Hospital in Spain.  Almost half of the people with RLS have a relative also having the same condition.  RLS may also develop due to the following factors:

Helping You Get A Relaxing Sleep

Diagnosing restless leg syndrome isnt a complex process; its one sleep disorder with unique symptoms that your doctor will recognize.

Your specialist at Central Maine will help you find the right treatment, which may involve lifestyle changes such as cutting alcohol and tobacco use, setting and sticking to a regular sleep pattern and doing moderate exercise, including aerobics and leg stretching.

Iron supplements might also if a blood test shows youre iron-deficient. Your doctor might want to try anti-seizure medications, which increasingly are the first line of defense in treating restless leg.

For non-drug therapies, massaging your legs can soothe and relax your muscles, reducing the discomfort of restless leg. If the idea of massaging appeals to you, ask your doctor to look into new devices that wrap around the leg and vibrate, delivering relief to the muscles running down the back of your legs.

It couldnt be more aptly named: if you have Restless Leg Syndrome, it means your legs wont stay still. Also called Willis-Ekbom Disease, restless leg affects nearly 10 percent of adults in America. It happens at any age, to both men and women, and the discomfort happens more frequently and lasts longer as you get older.


Where Can I Get More Information

Triggers That May Worsen RLS

For more information on neurological disorders or research programs funded by the National Institute of Neurological Disorders and Stroke, contact the Institute’s Brain Resources and Information Network at:

Office of Communications and Public LiaisonNational Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesda, MD 20892

health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient’s medical history.

All NINDS-prepared information is in the public domain and may be freely copied. Credit to the or the is appreciated.

Medical Devices For Restless Legs Syndrome

New attention is being given to the possibility of using medical devices to improve RLS symptoms. Similar to the way that moving the legs gives temporary relief, these medical devices aim to reduce discomfort of RLS symptoms by providing external stimulation.

So far, the Food and Drug Administration has approved two medical devices as RLS treatments: a compression foot wrap and a vibrating pad. Both are available by prescription and designed for people with moderate to severe RLS.

The foot wrap works by applying targeted pressure to the affected area, usually the lower leg or foot. By contrast, the vibrating pad uses counter-stimulation to mask RLS symptoms and improve sleep quality. Both devices are considered fairly safe, though they may not be suitable for people with certain underlying health conditions.

Some physicians also recommend using a pneumatic compression device to ease RLS symptoms. Its thought that compression of the veins helps boost circulation and reduce the uncomfortable sensations caused by RLS.

Medications Aggravate Restless Leg Syndrome

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Restless Leg Syndrome Definition And Facts

  • Restless leg syndrome is a marked by a strong urge to mover the legs along with symptoms of unpleasant sensations in the legs while resting and sleeping, for example, tingling, burning, and aching, while resting. The condition also causes leg pain and .
  • Symptoms of restless leg syndrome are aching and an urge to move the lower extremities
  • It is suggested the main cause of restless leg syndrome is a problem using or the lack of iron in the . Many conditions have been associated with restless leg syndrome because of the iron problem, for example, , rheumatoid arthritis, , kidney failure, Parkinson’s , and iron deficiency.
  • Restless leg syndrome tends to run in families.
  • Restless leg syndrome frequency leads to .
  • Treatment and home remedies for restless leg syndrome include medications and home remedies to manage symptoms and leg , increase the amount and quality of , and treat underlying medical conditions.
  • Home remedies for restless leg syndrome include
  • iron supplementation for those that are iron deficient.
  • Restless leg syndrome is generally not considered , but treatments can substantially lessen or eradicate symptoms.
  • Other conditions that my mimic restless leg syndrome include poor circulation to the lower extremities, , and .
  • Women With Rls Are At Risk

    Now a new study has shown that middle-aged women with restless legs are at increased risk for developing high blood pressure.

    The study evaluated 65,544 women, ages 41 to 58, who were participating in Nurses’ Health Study II, one of the most thorough studies of women ever undertaken.

    Results showed that women who reported restless leg symptoms most frequently had higher systolic and diastolic blood pressure readings. Specifically:

    • The odds of hypertension increased by 26% for women who reported 5 to 14 incidences of RLS per month
    • These odds increased to 33% for women with more than 15 monthly restless leg symptoms
    • Women with no restless leg syndrome symptoms only had a prevalence of high blood pressure of 21%.

    How Effective Is Magnesium As A Restless Legs Syndrome Treatment

    Restless legs syndrome , also known as Willis-Ekbom Disease, is a nervous system disorder that gives patients an overwhelming urge to move their legs. The symptoms also include throbbing, pain, and other types of unpleasant and disturbing sensations in the legs.

    Symptoms of the syndrome are more pronounced when patients are sitting, laying down, sleeping, or otherwise inactive. It can be extremely disruptive to sleep and can lead to insomnia and chronic sleep deprivation.

    RLS is closely related to periodic limb movements during sleep . The only difference is that PLMS occurs only when the patient is sleeping, while RLS symptoms can show up while awake.

    What Are The Symptoms Of Restless Leg Syndrome

    The most prominent symptom of RLS is the uncontrollable movement of legs while you are still or lying on the bed. Here are other symptoms of restless leg syndrome.

    • Sensations in the legs when you begin resting.
    • Intense leg twitching especially in the evening.
    • Daytime sleepiness.
    • Reduced productivity due to poor sleeping patterns.
    • Goosebumps in the legs.
    • You find relief from these symptoms through walking, running, or having a warm shower.
    • Moodiness and hyperactivity.
    • Poor concentration during the day.

    Can Hydroxyzine Cause Restless Leg Syndrome


    Hydroxyzine, a medication with sedative properties,6-8 had been effective on RLS symptoms in Case 1. We observed a prompt remission of RLS symptoms . In both patients, the discontinuation of therapy after two months caused a recurrence of RLS symptoms.

    Furthermore, does mirtazapine cause restless legs? OBJECTIVE: Mirtazapine is known to often provoke restless legs syndrome . Concomitant medication with tramadol, non-opioid analgesics, antihistamine, and dopamine-blocking agents was more frequently prescribed in subjects developing mirtazapine-associated RLS.

    Similarly, what medications aggravate restless leg syndrome?

    certain medications that may aggravate RLS symptoms, such as antinausea drugs , antipsychotic drugs , antidepressants that increase serotonin , and some cold and allergy medications that contain

    Can venlafaxine cause restless leg syndrome?

    It is observed as a side effect related to the administration of antidepressants in 9% of patients. A case reporting restless legs syndrome symptoms associated with venlafaxine 75 mg/day is decribed. Based on this report, venlafaxine should be added to the list of agents that can induce restless legs syndrome.

    For Natural Restless Leg Syndrome Treatment Try The Following:

    News: Pediatric Neurology Epilepsy Sleep Medicine Brain ...

    • If you smoke tobacco, stop
    • Eliminate alcohol as it can aggravate restless leg symptoms
    • Gentle exercise may help; try yoga in the morning and evening
    • A daily walk can be helpful as a restless leg syndrome treatment
    • A healthy diet is essential
    • Several nutrients play a key role in helping to decrease restless leg syndrome symptoms. These are magnesium, B12, folic acid, vitamin D, iron , and vitamin C. Premium health supplements can help fill out all the gaps in your diet where nutrients may be missing.
    • Before sleep, gently massage your legs, starting at the ankles and working up
    • A bath, hot or cool, may help relieve some of the RLS symptoms.
    • Be aware of how caffeine effects you. Caffeine stays in the body a long time during the day, so if you must have caffeine, restrict it to before noon. A routine of a cup of coffee in the morning may or not be okay for you. It’s best to remove caffeine from your diet though.

    Restless Legs Syndrome Triggers

    You want to relax but your legs have other plans. Where does that creepy-crawly feeling come from? It could be iron deficiency, pregnancy or even weak veins. Here’s how to treat these common restless leg symptoms..

    Millions of women cant sit or lie still long enough to take a flight, see a movie, watch their daughters dance recital, make love or fall asleep.Blame restless legs syndrome , a neurological sleep and movement disorder that causes painful, crawling sensations in the legs and an irresistible urge to move them.For some women, the only solution is to walk all night, says Mark Buchfuhrer, M.D., an internist and pulmonary specialist at SomnoMedix Sleep Disorders Center in Los Angeles and co-author of .

    To isolate triggers, record your eating, exercise, medication and sleep habits in a diary and watch for patterns, Bainbridge says. If symptoms dont quit, see your doctor. You may need blood tests for iron deficiency, disease, kidney disease, liver disease and/or diabetes all of which are associated with RLS, says Dr. Buchfuhrer.Read on for 8 things that trigger restless legs syndrome symptoms and how to prevent them.Restless Legs Syndrome #1: MedicationThe most common RLS triggers are prescription and over-the-counter medications, Dr. Buchfuhrer says.Because they block dopamine, the worst culprits include:

    To Avoid a Flare:

    Restless Legs Syndrome #3: BoredomRLS symptoms

    To Avoid a Flare:

    To Avoid a Flare:

    Restless Legs Syndrome #7: Caffeine and Alcohol

    What Are The Symptoms Of Rls

    Symptoms usually start in the evening just as you sit down to relax, and may progressively worsen throughout the night. Both legs are usually affected although one may be worse than the other. In more severe cases, the arms and lower trunk may also be affected. RLS affects more than twice as many women as men.

    Four out of five people with RLS have PLMS as well. These twitchy movements can be so violent that they often jerk the person awake, making for an exhausting night and very little sleep!

    Chinese Herbs As An Excellent Restless Leg Treatment

    Herbal remedies are an incredibly efficient drug-free solution for the discomfort caused by restless leg syndrome. Herb-based formulas may help the kidneys and heart, which results in immediate relief of the uncomfortable sensations of RLS. Herbal remedies often include the muscle-relaxing and nerve-toning plants. The nerve-toners involve milky oats, gotu kola, and ashwagandha. These herbs have been widely used to treat nervous deficiency, reducing the signs of restless leg syndrome. Muscle-relaxing herbs may improve the quality of your sleep. A licensed Chinese herbalist may recommend passionflower, valerian, and kava. A Chinese herbalist will recommend the particular formula and the exact dosage you should follow. Although herbal remedies are generally safe and free of side effects, you shouldnt take them without consulting your practitioner. Certain herbs may interfere with the medications youre taking or are inadequate for your particular condition.

    What Research Is Being Done

    The mission of the National Institute of Neurological Disorders and Stroke is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. The NINDS is a component of the National Institutes of Health , the leading supporter of biomedical research in the world.

    While the direct cause of RLS is often unknown, changes in the brains signaling pathways are likely to contribute to the disease. In particular, researchers suspect that impaired transmission of dopamine signals in the brains basal ganglia may play a role. There is a relationship between genetics and RLS. However, currently there is no genetic testing. NINDS-supported research is ongoing to help discover genetic relationships and to better understand what causes the disease.

    The also supports research on why the use of dopamine agents to treat RLS, Parkinsons disease, and other movement disorders can lead to impulse control disorders, with aims to develop new or improved treatments that avoid this adverse effect.

    More information about research on RLS supported by or other components of the is available through the NIH RePORTER , a searchable database of current and previously funded research, as well as research results such as publications.

    What Should You Do With This Information

    First, understand there is an association between restless leg syndrome and high blood pressure in men also. Women, however, have a greater risk for developing RLS and more women do have restless leg syndrome symptoms. This is especially true for pregnant women.

    Second, it may be that ongoing restless leg syndrome treatment may help to reduce the incidence of hypertension. This in turn may help reduce stroke and heart attack risks and the devastation that both of these diseases cause.

    Clearly then, it’s important for men and women to keep their RLS and blood pressure under control.

    Tips For Coping With Restless Legs Syndrome

    Learning to recognize and avoid your personal triggers can help you manage RLS over time.

    Effective techniques for minimizing RLS symptoms vary from person to person. Many people find relief from keeping active throughout the day and using acupuncture, massage, stretching, or relaxation techniques at night. During the day, you may be able to ward off RLS symptoms by keeping your mind busy even when you are sitting still with activities like reading or chatting to a friend.

    Though RLS is not life-threatening, the frustration of not being able to sleep well can take a toll on mental health. Cognitive behavioral therapy, support groups, or reaching out to family and friends may provide additional emotional resources for coping with RLS.

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    What Is The Prognosis For People With Restless Legs Syndrome

    RLS is generally a lifelong condition for which there is no cure. However, current therapies can control the disorder, minimize symptoms, and increase periods of restful sleep. Symptoms may gradually worsen with age, although the decline may be somewhat faster for individuals who also suffer from an associated medical condition. A diagnosis of RLS does not indicate the onset of another neurological disease, such as Parkinsons disease. In addition, some individuals have remissionsperiods in which symptoms decrease or disappear for days, weeks, months, or yearsalthough symptoms often eventually reappear. If RLS symptoms are mild, do not produce significant daytime discomfort, or do not affect an individuals ability to fall asleep, the condition does not have to be treated.

    So What Are Your Options For Restless Leg Syndrome Treatment

    Treatment of Restless Legs Syndrome (RLS) in Older Adults #79

    Start by downloading the free e-book below called Natural Help for Restless Leg Syndrome. It gives you an overview of restless legs syndrome and options for treatment.

    The e-book focuses on natural restless leg syndrome treatments rather than drugs.

    Pharmaceuticals are way over prescribed for far too many health conditions. And they ALWAYS come with the risk of side effects, so first trying lifestyle changes is always a wise choice. Make no mistake however, I’m not against drugs; they do have their place in medicine.

    Also, restless leg syndrome treatment varies widely from individual to individual. For mild to moderate cases, drugs may be unnecessary.

    Therefore, I’m only focusing below on natural RLS treatment.

    Ruling Out Potential Causes

    Your first step in addressing RLS should be to figure out if something is causing it. While RLS can be related to things that are largely out of your control, such as genetics or pregnancy, other possible factors can be addressed.

    These factors could be daily habits, medications youre taking, health conditions you have, or other triggers.

    How To Stop Restless Legs With Acupuncture

    Certified acupuncturists apply mild and reducing techniques to ease your discomfort. Depending on your overall health and a particular condition, your practitioner may use different needling techniques and recommend the exact number of treatments you need to feel significant improvements. Acupuncture is rarely used as a stand-alone treatment, but practitioners usually combine it with herbal therapies to boost the overall effect. The right herbal therapy delivers significant improvements, and it is one of the safest treatments for different kinds of conditions, including RLS.

    Surgery For Varicose Veins


    Varicose veins are enlarged blood vessels, often in the legs, that overfill with blood. This increased amount of blood can lead to superficial venous insufficiency , which means your body cant properly circulate blood. As a result, the blood pools in your legs.

    In a 2008 study, 35 people with SVI and RLS had a procedure called endovenous laser ablation to treat their varicose veins. Of the 35 people, 84 percent of them had their RLS symptoms significantly improved or completely eliminated by the surgery .

    Again, more research is needed on this surgery as a treatment for RLS.


    If youre interested in any of these less-researched treatments, ask your doctor about them. Of course, you can try hot and cold treatments on your own, but your doctor can tell you more about the other treatments and whether they might be able to help you.

    How Does Cbd Manage The Symptoms Of Restless Leg Syndrome

    Despite RLS being present for a long time, it is only recently that people started using CBD products as a form of treatment for RLS symptoms. Previously, the common ways to treat manage RLS symptoms included taking hot baths, using medications, hot or cold compresses around your legs, massages, and conducting specific types of exercises. Studies now reveal that CBD can alleviate the symptoms of RLS.

    A conducted by the Center for Clinical Science on 6 patients shows that CBD oil can relieve the symptoms of RLS. These participants observed reduced intensity or disappearance of the RLS symptoms after using CBD oil.

    Research on the benefits of CBD to the body reveals that it is a muscle relaxant with powerful nerve-calming effects. It can be applied topically on the legs or taken orally to experience relief from your symptoms. Some people with RLS claim to have witnessed reduced sensations after using a CBD tincture under the tongue or applying topically on the legs before going to bed.

    It is not clear whether CBD ends up treating the underlying causes of the symptoms of RLS. But users have reported better sleeping patterns. More research needs to be conducted on the potential benefits of CBD to prove the claims that users make about it.

    Transcutaneous Electrical Nerve Stimulation

    With transcutaneous electrical nerve stimulation , a device sends small electrical currents to parts of your body to help relieve pain.

    Theres not a lot of research on the use of TENS to treat RLS, but it could work.

    The idea is that like the Relaxis vibrating pad, it uses counterstimulation. One study showed that regular use of TENS along with a vibration treatment completely relieved one mans RLS symptoms (

    However, more research is needed to confirm acupuncture as a reliable treatment for RLS.

    From Seed To Serum: How Cbd Products Are Made

    Cannabidiol is rapidly becoming a wonder drug that can help people manage conditions as disparate as menstrual discomfort and AIDS and there is some good initial research that indicates CBD isnt just a placebo. CBD interacts with the human endocannabinoid system, helping stimulate the body to heal itself in a way many other drugs

    Primary Or Idiopathic Rls

    Idiopathic means that the cause is unknown.

    It is the most common type and has the following characteristics:

    • It usually begins before the age of 40.
    • It can start as early as childhood.
    • It may have a genetic cause.
    • Once primary RLS starts, it tends to be lifelong.

    Symptoms may be sporadic, or gradually worsen and become more prevalent over time.

    In mild cases, the person may have no symptoms for a long time.

    What Antidepressant Does Not Aggravate Restless Leg Syndrome

    Medications shown to benefit idiopathic restless legs ...

    farmerswife over a year ago


    Guest over a year ago

    over a year ago

    In reply to marti on 2012-11-20 – click to read

    over a year ago


    I suddenly started with this RLS problem.  Then I checked out this site.  I quit the St. John’s wort I had been taking three times a day and the problem has subsided.  I was taking the Research Grade as prescribed.  So, It must be true  that something that affects seratonin which, I believe tamps down dopamine will do this.  It is scary.  As movement disorders from medication can become permanent.  I would stay away from Ldopa or the others that help RLS as they , as far as I can gather from reading about this up dopamine.  Maybe wrong, but experience is the best teacher.

    Trying to cope with mild depression and anxiety with upbeat thinking and exercise. 

    Once I took Celexa for six years and woke up one morning with my little finger on my right hand moving and it did not stop for days.  I took benedryl  finally and it stopped.  But, needless to say, this scared me big time.  Then I went to St. John’s Wort.  Must be careful with that too. 

    I quit all meds and am trying my best to get by without.  I know for some this is not easy.

    Good Luck To All Of You


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